To study the effect of Wuzi Yanzong Pills combined with Western medicine in the treatment of patients with anovulatory infertility.Methods:A total of 90 patients with anovulatory infertility admitted to Qingyuan Traditional Chinese Medicine Hospital from January 2019 to January 2020 were selected as the research objects and were randomly divided into a Western medicine group，a traditional Chinese medicine group and a combined group，with 30 cases in each group.Patients in the Western medicine group were treated with clomiphene citrate capsule，and patients in the traditional Chinese medicine group were treated with Wuzi Yanzong Pills，and patients in the combined group were treated with both methods above.The efficiency，endometrium and ovulation rate were compared among in the 3 groups.Results:After treatment，the total effective rates of combined group，traditional Chinese medicine group and Western medicine group were 93.33%，66.67% and 73.33% respectively.There was significant difference among 3 groups(P<0.05).The endometrium in the combined group and the traditional Chinese medicine group was obviously thickened(P<0.05).The periodic ovulation rates of combined group，Chinese medicine group and Western medicine group were 74.05%，49.65% and 62.16% respectively.There was a statistically significant difference in ovulation rate among the 3 groups(P<0.05).After treatment，BBT scores of biphasic patients in the combined group increased，pregnancy rate increased，CMS scores increased.Those were better than those in the traditional Chinese medicine group and Western medicine group，and the difference was statistically significant(P<0.05).Conclusion:Wuzi Yanzong Pills combined with clomiphene citrate capsule can significantly improve ovulation rate，pregnancy rate，endometrial thickness，BBT distribution and CMS of anovulatory infertility patients，and the distribution is better than that of traditional Chinese medicine only or Western medicine only.