Migraine is related to stroke，especially ischemic stroke.This paper analyzed the pathogenesis of migraine related ischemic stroke from the perspective of traditional Chinese medicine(TCM).It is found that the location of migraine related ischemic stroke is in the liver while acute stage is due to the disorder of qi movement which closely related to liver.Liver wind invading collaterals is its core pathogenesis，and the final pathological outcome is cerebral collateral stasis and brain marrow deprived of nourishment.