To improve the quality standard of Mongolian medicine sirixi.Methods:Microscopic and TLC identification method was used to distinguish Radix et Rhizoma Rhei,Radix Inulae,Han Shuishi,Rhizoma Kaempferiae,Semen Momordicae,Shiliu,Hei Bingpian in Mongolian medicine sirixi for microscopy and thin layer chromatography.Emodin in Rad ix et Rhizoma Rhei was determined by High Performance Liquid Chromatography.Results:The microscopic identification feature pictures of Sirixis were clear,and the thin-layer identification had clear spots of the same color at the positions corresponding to the spots of Radix et Rhizoma Rhei,Radix Inulae,and Rhizoma Kaempferiae reference substances,negative and no interference.Emodin has a good linear relationship with the peak area in the range of 0.001 7 to 0.135 2 mg/mL (r=0.999 8),the average recovery rate was 102.15%,and the average content was 0.105 5 mg/g.Conclusion:The method can be used to distinguish Mongolian medicine sirixi for its quality control.