To summarize the diagnosis experience of Tibetan doctors in the treatment of “Huang-shui” disease, and to analyze the rules of the use of Tibetan medicine in the treatment of “Huang-shui” disease by combining the theories of Tibetan medicine. Methods:In combination with the experience in the diagnosis and treatment of “Huang-shui” disease in the Traditional Tibetan medicine works Four Medical Classics and Crystal Pearl Materia Medica, the search terms of “Huang-shui” disease and dry “Huang-shui” were used to screen the three “Huang-shui” prescription for the treatment of “Huang-shui” disease from the self-established Tibetan medicine prescription preparation knowledge base. The word frequency analysis and co-occurrence analysis were completed, and the data were exported to Cytoscape 3.7.1 for visual network analysis. Under the guidance of Tibetan medicine theory, the compatibility rules of three “Huang-shui” prescription were explored, and the dominant diseases of Tibetan medicine in treating “Huang-shui” disease. were analyzed. Results:A total of 12 prescriptions with 81 Tibetan medicines were retrieved for the treatment of “Huang-shui” disease. The “San-huang-shui” remedies (Po-ga, Huang-quai-zi, Semen Cassiae) were most often combined with Fructus Chebulae, Radix Aucklandiae, Maokezi, Yu Ganzi, Moschus, Semen Myristicae, Fructus Tsaoko, Kuanjinteng, Flos Caryophylli, Baxiaga. Among them, “San-guo” (He-zi, Mao-he-zi and Yu-gan-zi) can clear blood heat and dissolve bad blood; with pungent and warm wood, Radix Aucklandiae, Moschus, Semen Myristicae and Flos Caryophylli, etc. were mainly used to treat cold “huang-shui” disease, while with Kuan-jing-teng and Ba-xia-ga,etc., which can clear “Chi-ba” heat, are mainly used to treat hot “Huang-shui” disease. Conclusion:Tibetan medicine follows the diagnosis and treatment mode of combining diseases and illnesses to treat “Huang-shui” disease, and the “San-huang-shui” prescriptions are the core collection of formulas used to treat “Huang-shui” disease, and rheumatoid arthritis and atopic dermatitis belong to the advantageous diseases treated by the “San-huang-shui” prescriptions.