A decision tree is called this name because it is shaped like a tree and it can be used for decision-making.It is a set of hierarchical rules inferred from a series of disordered and irregular logical relations by machine learning，and the outcomes are expressed according to the tree graph of probability distribution，so as to accurately predict or correctly classify.This paper systematically summarizes the present situation of the application of decision tree in the field of traditional Chinese medicine，and found that the decision tree in used in disease risk assessment，diagnosis of TCM diseases and syndromes，syndrome differentiation of TCM，the prediction of Chinese medicinal properties or adverse reactions，syndrome differentiation associated with physical and chemical indicators，prognostic evaluation and cost effect analysis and so on.The classification and prediction results by decision tree are more accurate，and is worth for further research and application in the future.