To observe the clinical efficacy of modified Erxian decoction combined with electrical stimulation on postoperative recovery of patients with spinal cord injury.Methods:A total of 96 patients with spinal cord injury admitted to The Second Affiliated Hospital of Air Force Military Medical University from January 2017 to December 2018 were selected as the research subjects，and according to the random number table method，they were randomly divided into a control group and an observation group with 48 in each group.All patients were treated with surgical decompression，open reduction and internal fixation of fractures.The control group received electrical stimulation on the basis of prior routine treatment，while the observation group received modified Erxian decoction on the basis of the control group intervention.Before treatment and 6 months after treatment，the clinical efficacy，Barthel Index(BI) life ability assessment，American Spinal Injury Association(ASIA) neurological function score，visual analog scale(VAS) score and other changes were regularly evaluated.The serum levels of tumor necrosis factor-α(TNF-α)，interleukin-1β(IL-1β)，interleukin-8(IL-8) and C-reactive protein(CRP) were monitored pre-operatively and at 1-week follow-up.The serum levels of nerve growth factor(NGF) and brain-derived neurotrophic factor(BDNF) were measured pre-operatively and at 6-month follow-up.Results:Compared with before treatment，the clinical efficacy，Barthel Index，ASIA nerve function score and VAS score of 2 groups were significantly improved after treatment(P<0.05).Additionally，these clinical indicators in the observation group were better than those in the control group，and the difference was statistically significant(P<0.05).After treatment the levels of inflammatory response factors TNF-α、IL-1β、IL-8、CPR in the 2 groups were significantly decreased，and the levels of neurotrophic factors(NGF) and BDNF were significantly increased，and the difference was statistically significant(all P<0.05).The improvement in the observation group was significantly better than that in the control group，and the difference was statistically significant(P<0.05).Conclusion:Modified Erxian decoction combined with electrical stimulation is effective in postoperative recovery of spinal cord injury，which provides great clinical values.The effects of modified Erxian decoction on spinal cord injury is related to the decrease of inflammatory reaction and the increase the level of neurotrophic factor.To probe into the mechanism on modified Erxian decoction combined with electrical stimulation comprehensively is of great importance in optimizing this prescription and therapeutic schedule on patients with spinal cord injury.