To investigate the mechanism of Fujian Tablets in the treatment of ischemic stroke(IS) with the help of Internet pharmacology platform technology.Methods:TCMSP，TCMID and Batmann-TCM databases were used to screen the active components and their targets of Polygonum multiflorum，sangjis-heng，Cassia obtusifolia，epimedium and hippocampus in Fujian Tablets;the target information in Fujian T-ablets was proofread by UniProt database; the disease target genes of IS were obtained by GeneCard-s database; Cytoscape 3.7.2 software and STRING 11.0 database were used to construct PPI network and conduct bio-enrichment analysis.Results:A total of 45 active components and 144 targets were obtained，including IL6，IL1 β，TNF，VEGFA，NOS3，etc.; 1485 IS related targets; 300 GO biological processes and 84 related signal pathways were obtained，involving PI3K-AKT signaling pathway，TNF signaling pathway，cGMP-PKG signaling pathway，cAMP signaling pathway，NF-κB signaling pathway，etc.Conclusion:Fujian Tablet through the mechanism of multi-component，multi-target，multi-channel interaction can achieve the purpose of treating IS.This research provides theoretical support for the further clinical application of Fujian tablets，and provides ideas for future experimental research.