To establish quality standards for Garixi Powder.Methods:Microscopic identification was used for qualitative determination of rhubarb,fructus chebulae,elecampane inula root,black borneol,fructus amomi rotundus,piperis longi,rhizoma kaempferiae and punica granatum.Thin layer chromatography was applied for qualitative determination of piperis longi,rhubarb,and fructus forsythiae.Physical and chemical identification was used for qualitative determination of sodium carbonate decahydrate.High performance liquid chromatography was used for quantitative determination of free chrysophanol in thepowder.Results:The microscopic determination features were obvious and exclusive.TLC chromatographic spots were clear,and there was no interference for negative samples.A good linearity of chrysophanol was shown in range of 47.45~189 8 ng(r=1) with high performance liquid chromatography.The average recovery of chrysophanol was 97.08%,and the RSD was 1.12%(n=6).Conclusion:The methods in this research are simple,sensitive,accurate,and with good reproducibility.It can be used for quality control of Garixi Powder.