基于国内外指南的盆腔炎症性疾病中西医诊疗
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国家自然科学基金重点项目(81830115)


Chinese and Western Medicine Diagnosis and Treatment of Pelvic Inflammatory Diseases Based on Domestic and Overseas Guidelines
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    摘要:

    目的:比较分析国内外关于盆腔炎症性疾病(Pelvic Inflammatory Disease,PID)的中、西医指南内容,为优化PID中西医结合诊疗提供参考。方法:检索国内外电子数据库与相关指南网站,纳入截至2020年2月17日最新版PID指南,对PID的诊断标准、治疗原则、抗菌药物方案及其耐药性等进行比较分析。结果:最终纳入国内外发布的6个最新PID指南,西医指南包括(中国、法国、美国疾病控制与预防中心、英国性健康与艾滋病协会、欧洲国家等),中医指南为我国本土指南。在诊断标准方面,国内外西医指南均支持将诊断PID的门槛保持在较低水平,中医指南以中医与西医诊断标准为依据,确定了不同分型及其治则;在治疗方面,西医指南对广谱抗生素联合的治疗原则一致,用药与疗程不尽相同,此外国外指南均提及喹诺酮类等抗菌药物耐药情况及不良反应。中医指南对PID中医药疗法进行了规范,提出以美国指南抗生素治疗为基础、中医药单用/联合抗生素的中西医结合原则,但单用中医药治疗目前仍缺乏充足高质量的证据。没有中西医结合的具体处方的指南内容。结论:我国目前缺少对治疗PID的抗菌药物的耐药情况评价;中西医结合治疗PID是我国优势,但尚需要更多循证医学证据支持;未来有必要制定建立在我国本土抗生素方案的证据上、有机结合地中西医结合具体治疗方案。

    Abstract:

    To compare and analyze the contents of Chinese and Western medicine guidelines on pelvic inflammatory disease(Pelvic Inflammatory Disease,PID) at home and abroad,and to provide reference for optimizing integrated Chinese and Western medicine diagnosis and treatment on PID.Methods:Domestic and foreign electronic databases and related guide websites were searched,the latest PID guidelines as of February 17,2020 were included.Then the diagnostic criteria,treatment principles,antibacterial drug regimens and drug-resistant of PID were analyzed and compared.Results:Finally,6 latest PID guidelines issued at home and abroad were included.Western medicine guidelines included China,France,American CDC,Britain BASHH,and European STI etc.,and TCM guidelines were local guidelines in our country.For the diagnostic criteria,both domestic and foreign western medicine guidelines supported keeping the threshold for diagnosing PID at a low level.The TCM guidelines determined classifications and treatment rules based on the diagnostic criteria of TCM and Western medicine(WM).For treatment,the western medicine guidelines were consistent with treatment principles of the broad-spectrum antibiotic combination,but the medication and course of treatment were not exactly the same.In addition,foreign guidelines all mentioned antimicrobial resistance and adverse reactions of quinolones and other antimicrobial drugs.The TCM guidelines regulated the practices of TCM on PID,and proposed the principle of integrated TCM and WM:based on American CDC,TCM alone/combined antibiotics.However,the practice of TCM alone still lacked sufficient high-quality evidence.Any specific prescription recommendations or guidelines for integrating TCM and WM had not been found.Conclusion:Currently,China lacks the evaluation of resistance to antimicrobial drugs for the treatment of PID.Integrating TCM and WM in the treatment of PID is an advantage of China,but more evidence-based medical evidence is needed for support.In the future,it is necessary to formulate specific therapy protocols for organically integration of TCM and western medicine,based on the evidence from China's local antibiotic program.

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李玉琦,宫艺,梁士兵,沈文娟,刘建平.基于国内外指南的盆腔炎症性疾病中西医诊疗[J].世界中医药,2021,(19).

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  • 收稿日期:2020-07-17
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  • 在线发布日期: 2021-11-05
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