Prostate cancer is a common male malignancy.The androgen deprivation therapy is the cornerstone of the treatment of medium and high-risk prostate cancer.However，while controlling tumors，it also causes dysfunction of the body's nervous，immune，and endocrine systems，resulting in a series of side effects such as fatigue，hot flashes，osteoporosis，and decreased sexual function，which are collectively referred to prostate cancer castration syndrome.As a key factor affecting the quality of life of prostate cancer patients，castration syndrome has attracted widespread attention in the medical community.Based on the summary of previous studies，this article proposes to use the heart-liver-kidney axis of TCM as the entry point to adjust the viscera function and restore the body's internal environment balance.At the same time，from the perspective of quality of life assessment，combined with the Functional Assessment of Cancer Therapy-Prostate(FACT-P)carry out clinical research and analysis on castration syndrome，and continuously improve the efficacy of traditional Chinese medicine in the prevention and treatment of castration syndrome through multi-level treatment methods，and construct the ideas and methods of traditional Chinese medicine for the treatment of castration syndrome in prostate cancer.