“Three spirits” syndrome differentiation of insomnia has been developed for more than 30 years.At present，it has formed a treatment system that integrates theory，syndrome differentiation，evaluation，treatment principles and methods，efficacy verification and equipment research and development in TCM psychotherapy of insomnia.This paper introduced the syndrome differentiation theory of “three spirits” in insomnia，definition and functions of “primordial spirit”,“thinking spirit”and“desire spirit” in insomnia，as well as pathology and pathogenesis.“Three spirits” syndrome differentiation method is personality tendency，with focus on insomnia symptom and emotion.It compiled the evaluation tools of Wang Insomnia Integrated Questionnaire（WIIQ） and Wang's Personality Trend Inventory(WPTI) under the guidance of its theory.Diagnosis and treatment based on overall analysis of symptoms and signs of insomnia by “three spirits” are concentrating spirit，regulating spirit and abusing spirit.And the main treatment method is TIP sleep regulation technology including seven factors：low impedance construction technology；sleep cognition introduction technology，sleep environment adaptation technology，sleep attribution stripping technology，sleep confidence enhancement technology，sleep experience technology，and stop medication technology.Its clinical operation process mainly includes：medical history collection，related examination，diagnosis and treatment based on syndrome differentiation.In order to better study，apply，popularize and facilitate the treatment of self-intelligence，the team has also compiled an information module based on syndrome differentiation treatment technology of insomnia “three spirits”，with a multifunctional treatment equipment and an insomnia treatment APP developed.