to analyze the mechanism of Xiaoqinglong Decoction in the treatment of chronic obstructive pulmonary disease(COPD) by network pharmacology.Methods:the active ingredients and targets of Xiaoqinglong Decoction were searched in TCMSP database platform，and the traditional Chinese medicine compound target gene network was drawn to screen the key compounds; the COPD disease genes were searched by genecards and OMIM database; the Wayne map was drawn to obtain the drug disease common gene; the PPI protein interaction network was drawn by Xiaoqinglong Decoction COPD drug disease common gene Go functional annotation and KEGG pathway enrichment analysis were performed on the core genes.Results:137 active components of Xiaoqinglong decoction，188 potential targets，6949 targets related to COPD and 160 common targets of Xiaoqinglong Decoction COPD were obtained，which were mainly enriched in 92 biological processes and 49 signal pathways.Conclusion:Many drugs in Xiaoqinglong Decoction contain kaempferol，quercetin,(+)-catechin，stigmasterol，β-sitosterol and other components，which can act on AKT1，IL6，mapk1，PTGS2，TP53 and other core genes，regulate oxidative stress response，platelet α-granule and other biological processes，participate in the regulation of HIF-1，PI3K Akt signaling pathway，intervene in oxidative stress response and inflammatory response，and produce high yield Through the above process，it participates in the inflammatory reaction and oxidative stress process of COPD.