Chronic heart failure (CHF) is the final stage in the progression of heart disease caused by multiple factors and is a major contributor to reduced quality of life and death.The main symptoms were dyspnea，asthenia，edema，and decreased activity endurance.At present，the treatment of CHF is dominated by improving clinical symptoms，improving quality of life，reducing patients' repeated visits，and decreasing mortality.Although the pathogenesis of CHF is complex，abnormal energy metabolism in myocardial mitochondria is critical in the progression of heart failure.In recent years，understandings on myocardial mitochondrial energy metabolism in CHF have gradually deepened along with continuous research.More scholars of traditional Chinese medicine (TCM) have carried out a series of research on the treatment of heart failure with Chinese medicine based on the theory of mitochondrial energy metabolism，and made great achievements.The present study made a comprehensive elaboration on this aspect to deepen the understanding of medical workers on the treatment of heart failure by TCM.