基于肺络理论论治肺结节病
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国家中医药管理局中医络病重点学科建设项目(T0302);辽宁省“兴辽英才计划”高水平创新团队项目(XLYC1808011);辽宁省科学技术计划项目(2019JH2/10300023);辽宁省教育厅科学研究项目(2100221074);辽宁省教育厅科学技术研究项目:基于肺络构效理论参龙煎剂干预IPF代谢组学研究(L202067);沈阳市中青年科技创新人才支持计划:基于TGF-β1/Smads信号传导通路的清络饮干预特发性肺纤维化急性加重细胞凋亡机制研究(RC200156);国家自然科学基金青年科学基金项目(82004294)


Treatment of Pulmonary Sarcoidosis Based on Lung Collateral Theory
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    摘要:

    随着肺结节病发病率及检出率的逐年上升,肺结节病逐渐引起各界的关注及重视,对肺结节病CT随访期进行有效的干预治疗,延缓进展,控制生长,以致消除结节,是现代医学面临的关键问题。从肺络论治肺结节病,着手于肺络之内涵、结构、生理特点等,进而探究肺络虚损是肺结节病的病理基础、肺络-气机失调是肺结节病发生的病理环节、肺络-气郁痰瘀停聚是肺结节病的重要病理演变、肺络郁闭是肺结节病的基本病机。最终,立足于中医络病理论的优势,提出通络法论治肺结节病,以期为临床论治肺结节打开新的诊疗思路,提供新的理论认识。

    Abstract:

    With the increasing incidence and detection rate of pulmonary sarcoidosis,pulmonary sarcoidosis has gradually attracted attention of all circles.Effective intervention in pulmonary sarcoidosis during CT follow-up,delaying its progression,controlling its growth,and eliminating nodules are the key issues of modern medicine.The present study discussed the treatment of pulmonary sarcoidosis based on the lung collateral theory from the connotation,structure,and physiological characteristics of lung collaterals.As explored,the deficiency and injury of lung collaterals is the pathological basis of pulmonary sarcoidosis; the imbalance of qi movement in lung collaterals is the pathological link; qi depression and phlegm stagnation and accumulation in lung collaterals are important pathological evolution; depression and blockage in lung collaterals is the basic pathogenesis.Finally,by virtue of the advantage of the collateral disease theory in traditional Chinese medicine(TCM),this study proposed the method of dredging collaterals in the treatment of pulmonary sarcoidosis to provide a new diagnosis and treatment idea and theoretical understanding for the clinical treatment of pulmonary nodules.

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王铭钧,庞立健,吕晓东,王琳琳,王铭竹,臧凝子,史雁南,张耀艺,李斯宇.基于肺络理论论治肺结节病[J].世界中医药,2022,(10).

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  • 收稿日期:2021-03-30
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  • 在线发布日期: 2022-06-27
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