Traditional Chinese medicine(TCM) master professor Lyu Renhe proposes the basic pathogenesis of “micro-abdominal mass” for chronic kidney diseases，with the treatment following the principles of replenishing qi，nourishing blood，activating blood，and excreting water，and employs the herbal pair Ganoderma-Salviae Miltiorrhizae Radix et Rhizoma to treat various chronic kidney diseases.In the nephrotic syndrome(NS)，Prof.Lyu combines the herbal pair with Polyporus，Notopterygii Rhizoma et Radix，Alpiniae Oxyphyllae Fructus，etc.to assist glucocorticoids in toxicity reducing and efficacy enhancing based on the pathophysiological and pharmacological findings.In IgA nephropathy，Prof.Lyu advocates cooling and activating blood to dispel pathogenic factors based on the importance of tonifying lung qi，reinforcing healthy qi，and consolidating the root.