To explore the distribution characteristics of traditional Chinese medicine(TCM) syndromes in hepatitis B cirrhosis by a single arm Meta-analysis.Methods:China National Knowledge Infrastructure(CNKI),Chinese Biomedical Literature Database(CBM),China Science Periodical Database(CSPD),Chinese Citation Database(CCD),PubMed,EMBASE,Web of knowledge and Cochrane library were searched by computer from January 1,1963 to June 30,2020.Two researchers independently screened the literature according to inclusion and exclusion criteria,and extracted and cross-checked relevant research information.Agency for Healthcare Research and Quality(AHRQ) scale was used for quality assessment of included cross-sectional studies.The single arm Meta-analysis of TCM syndromes in hepatitis B cirrhosis was performed by Stata 16.0.Results:A total of 35 articles were included,33 in Chinese and 2 in English,involving 4,805 hepatitis B cirrhosis patients and 11 main TCM syndromes.Specifically,8 of the 11 syndromes could be subjected to Meta-analysis for distribution frequency,which were as follows:The syndrome of liver qi depression was 0.22 （95%CI 0.18 to 0.26,P<0.01),the syndrome of water-dampness internal obstruction was 0.19 (95%CI 0.14 to 0.24,P<0.01),the syndrome of dampness-heat accumulation was 0.22 (95%CI 0.19 to 0.25,P<0.01),the syndrome of liver-kidney yin deficiency was 0.19 (95%CI 0.19 to 0.24,P<0.01),the syndrome of static blood obstructing collaterals was 0.16 (95%CI 0.12 to 0.21,P<0.01),the syndrome of spleen-kidney yang deficiency was 0.11 (95%CI 0.09 to 0.14,P<0.01),the syndrome of liver depression and spleen deficiency was 0.32 (95%CI 0.14 to 0.50,P<0.01),and the syndrome of spleen deficiency and exuberant dampness was 0.16 (95%CI 0.13 to 0.19,P<0.01).Subgroup analysis demonstrated that there were statistically significant differences in the distribution of the syndromes of dampness-heat accumulation,liver-kidney yin deficiency,liver qi depression and water-dampness internal obstruction between southern and northern regions.Conclusion:The highest proportion of TCM syndromes in hepatitis B cirrhosis were liver depression and spleen deficiency,liver qi depression and dampness-heat accumulation,which showed the characteristics of the syndrome distribution to a certain degree.Additionally,the distribution of the four syndromes was different in different regions.