中医外治法改善失眠症睡眠质量的网状Meta分析
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辽宁省重点研发计划项目(2020JH2/10300070)


Improvement of Sleep Quality of Insomnia Patients with External Treatment of Traditional Chinese Medicine:A Network Meta-analysis
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    摘要:

    目的:采用网状Meta分析方法评价中医外治法治疗失眠症的疗效。方法:检索国家知识基础设施数据库(CNKI)、中国学术期刊数据库(CSPD)、中文科技期刊数据库(CCD)、中国生物医学文献数据库(CBM)、Embase、Cochrane图书馆、Web of Science、PubMed,收集中医外治法治疗失眠症的随机对照研究,并对纳入的研究进行质量评价和数据提取,检索时间从建库至2020年9月2日,使用Revman5.3软件、Stata/SE 15.0软件及频率学方法进行数据分析。结果:最终纳入25篇文献,6种中医外治法,共1 796例患者。网状Meta分析结果显示:推拿、电针、针刺、足浴、温针灸与口服艾司唑仑片比较,在改善失眠患者睡眠质量的效果方面差异有统计学意义,推拿与针刺比较、电针与温针灸比较、针刺与温针灸比较差异有统计学意义,其他比较均无统计学意义;累积排名曲线下面积由高到低排序为:温针灸、足浴、推拿、电针、耳穴压贴、针刺、艾司唑仑片。结论:中医外治法改善失眠症效果显著,温针灸成为最佳治疗方法的可能性最大,本研究因纳入文献的数量及质量的原因,结论仍需更多高质量、大样本、涵盖多种中医外治法的临床研究给予证实。

    Abstract:

    To evaluate the curative effect of external treatment of traditional Chinese medicine(TCM) on insomnia by network Meta-analysis.Methods:China National Knowledge Infrastructure(CNKI),Wanfang Data,China Biomedical Literature Database(SinoMed),VIP,Embase,Cochrane Library,Web of Science,and PubMed were searched to collect randomized controlled trials(RCTs) on treatment of insomnia with TCM external treatments from the inception of the databases to September 2,2020.The quality of the included studies was evaluated and data were extracted.Revman 5.3 and Stata/SE 15.0 were used for data analysis with the frequency method.Results:A total of 25 articles and 6 TCM external treatments were finally included,involving 1 796 patients.Network Meta-analysis showed that tuina,electroacupuncture,needling,foot bath,and warming needle moxibustion were significantly different from oral estazolam tablets in improving the spleen quality of insomnia patients; significant differences were also observed between tuina and needling,electroacupuncture and warming needle moxibustion,needling and warming needle moxibustion; there was no difference between other treatments.The surface under the cumulative ranking curve(SUCRA) value was ranked from high to low as follows:warming needle moxibustion,foot bath,tuina,electroacupuncture,auricular point pressing,needling,estazolam tablets.Conclusion:TCM external treatments had significant effect in improving insomnia,and warming needle moxibustion had the highest possibility of becoming the optimal treatment method.Due to the quantity and quality of the included literature,the conclusion still needs to be confirmed with more high-quality,large-sample clinical studies covering a variety of TCM external treatments.

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高璐,孔德昭,王思佳,张哲.中医外治法改善失眠症睡眠质量的网状Meta分析[J].世界中医药,2022,(19).

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  • 收稿日期:2020-11-30
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  • 在线发布日期: 2022-11-14
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