To explore the treatment laws of endometriosis disease treated by contemporary doctors based on the Ancient and Modern medical Case Cloud Platform.Methods:The papers on the syndrome differentiation and treatment of endometriosis(EM) and adenomyosis(AM) were collected from China National Knowledge Infrastructure(CNKI)，China Science Periodical Database(CSPD)，and Chinese Citation Database(CCD) from the establishment of the database to April 30，2020.The Syndrome types and prescriptions of traditional Chinese medicine(TCM) were collected and screened out to establish and standardize the database.The Ancient and Modern medical Case Cloud Platform was used to carry out frequency statistics of TCM syndrome types.The frequency，nature-flavor meridian，association rules，cluster analysis，and complex network analysis of TCM prescriptions were mined.Results:1)TCM syndrome types：Qi stagnation and blood stasis type was the most common type of EM，and cold coagulation and blood stasis type and kidney deficiency and blood stasis type were the most common in AM. 2)Medication rules：The high-frequency drugs for EM were Angelicae Sinensis Radix，Chuanxiong Rhizoma，Paeoniae Radix Rubra，etc.，and the high-frequency drugs for AM were Corydalis Rhizoma，Poria，Paeoniae Radix Rubra，etc.The properties of both drugs for EM and AM were warm，mild，and mildly cold，and meridian tropism was mainly distributed in the liver，spleen，kidney，and heart meridian.The drugs for EM were mainly bitter in flavor，and those for AM were mainly sweet，bitter，and pungent in flavor.Angelicae Sinensis Radix-Chuanxiong Rhizoma was the commonly-used compatibility for the treatment of EM，and Cinnamomi Ramulus-Poria was the commonly-used compatibility for AM.The core prescriptions were all based on the modification of Guizhi Fuling Pillls and Sanling Pills.Angelicae Sinensis Radix，Chuanxiong Rhizoma，and other qi-regulating and blood-activating drugs were commonly combined to treat EM，and Astragali Radix and other tonifying products were mainly added to treat AM.Conclusion:The treatment of endometriosis disease by contemporary doctors is based on promoting blood circulation and removing blood stasis with different emphases.The treatment of EM is mainly based on regulating qi and removing blood stasis，paying attention to emotional factors，and using qi-promoting and blood-activating drugs.Based on activating blood and resolving mass，the treatment of AM pays attention to hemostasis and tonic deficiency and should be compatible with drugs for tonifying kidney and qi and removing blood stasis and hemostasis.