Fresh Chinese herbal medicines with fresh juice，pure taste，and unique therapeutic effect have attracted wide attention of doctors of all generations.With the progress in modern science and technology and the increasing clinical demand，how to apply and promote fresh Chinese herbal medicines has become a research hotspot.Through systematic analysis，we divided the development history of fresh Chinese herbal medicines into five stages：emergence，development，maturity，flourishing，and reform.According to the current development status，we put forward six major development paths：improving quality standards，strengthening basic research，innovating fresh medicine preparations，developing fresh-keeping technology，expanding fresh medicine varieties，and building a complete fresh medicine industry chain.The aim is to inherit the original thinking and excellent experience of the ancients and promote the progress of the innovative cause of traditional Chinese medicine.