To explore the influence of meteorological factors on delayed onset of urticaria.Methods:The daily data of urticaria cases in four hospitals and meteorological data in Tianjin from January 2015 to December 2020 were collected.Spearman's correlation analysis and distributed lag non-linear model(DLNM) were used to analyze the influence of meteorological factors on delayed onset of urticaria.Statistical analyses were performed using SPSS 21.0 and R 3.5.1.Results:Two peak values were observed in the number of medical consultation on urticaria in Tianjin in the Beginning of Autumn and the End of Heat,while the trough values occurred in Greater Cold and the Beginning of Spring.The number of urticaria cases was positively correlated with average temperature(rs=0.361),relative humidity(rs=0.095),sunshine duration(rs=0.124),maximum temperature(rs=0.359),and minimum temperature(rs=0.352)(P<0.05),while negatively correlated with average wind speed(rs=-0.048)(P<0.05).The delayed onset of urticaria reached the peak under the average temperature at 27.5~30 ℃,relative humidity of 30%~35%,precipitation of 6~10 mm,sunshine duration of 0 h,and when the lag time was 0 solar term,0 solar term,0.5~1.3 solar terms,and 2 solar terms.The delayed effect showed two peaks when the average wind speed was 2~2.5 m/s and 4 m/s,and the lag time was 2 solar terms and 1 solar term,presenting a double peak trend.Regarding the relationship between delayed effect of various meteorological factors and onset of urticaria,the delayed effect of average temperature at 28 ℃ reached the highest with 0 solar term lag [relative risk(RR):1.660,95%CI 1.077 to 2.558,P<0.05)]; the delayed effect of average temperature at -2.8 ℃ reached the lowest with 0 solar term lag (RR:0.631,95%CI 0.416 to 0.960,P<0.05); the delayed effect of average wind speed of 3.0 m/s reached the lowest with 0 solar term lag (RR:0.836,95%CI 0.726 to 0.963,P<0.05).Conclusion:Meteorological factors such as average temperature,relative humidity,precipitation,average wind speed,and sunshine duration had a certain impact on the incidence of urticaria,among which precipitation,average wind speed,and sunshine duration affected the delayed onset of urticaria; especially average wind speed had the longest impact.