To analyze the characteristics of volatile components in Folium Artemisiae Argyi from Shaanxi Province.Methods:Gas chromatography-mass spectrometry(GC-MS) was carried out to identify the volatile components in 21 batches of Folium Artemisiae Argyi from Shaanxi Province and Qichun City.Clustering analysis,principal component analysis,and partial least squares-discriminant analysis(PLS-DA) were performed to sort the samples from Shaanxi Province and Qichun City.In the end,PLS-DA was used again to screen the main active components of Folium Artemisiae Argyi.Results:Thirteen common active components between Folium Artemisiae Argyi from Shaanxi Province and Qichun City were preliminary identified.Clustering analysis showed that samples from Qichun City and most samples from Shaanxi Province were in the same clade.Principal component analysis and PLS-DA results both indicated similar overall characteristics of the 13 volatiles.Principal component analysis of the common components suggested that eucalyptol,α-caryophyllene,humuleno,caryophyllene oxide,α-pinene,longum,thujone,menthol,eugenol,and α-terpineol may explain the 87.09% of the variance of Folium Artemisiae Argyi from Shaanxi Province.Conclusion:There were no significant differences in overall characteristics of the thirteen common volatile components in Folium Artemisiae Argyi from Shaanxi Province and Qichun City and the characteristic volatile components in Folium Artemisiae Argyi from Shaanxi Province were eucalyptol,α-caryophyllene,humuleno,caryophyllene oxide,α-pinene,longum,thujone,menthol,eugenol,and α-terpineol.