To analyze the research hotspots and trends of Tibetan medicine in the past 60 years，to better understand the research status and future development direction of Tibetan medicine.Methods:With Tibetan medicine as the research topic，the articles in China National Knowledge Infrastructure(CNKI) from January 1960 to December 2020 were searched.The published articles were counted.The cooperative network analysis of authors and institutions was carried out using CiteSpace and VOSviewer，and the keywords were analyzed by co-occurrence analysis，cluster analysis as well as topic path and burst term analysis.Results:A total of 6 282 articles were included，and the number of articles increased rapidly in the past 10 years，with the average publication number of 345.And 8 122 authors were included，involving 384 research institutions，which was represented by the team of Zhang Yi from the School of Ethnic Medicine，Chengdu University of Traditional Chinese Medicine.A total of 9 347 keywords were obtained，and cluster analysis revealed that the main research direction was related to literature research represented by Medical Canon in Four Sections(Si Bu Yi Dian)，clinical efficacy，chemical composition and plant resources in Tibetan areas.Conclusion:At present，the research of Tibetan medicine is on the rise overall，with stable research teams and mature research themes formed.We should carry out high-quality clinical research and mechanism exploration through inter-team cooperation and complementary advantages，to promote the all-round development of Tibetan medicine.