The thought of treating disease before its onset in traditional Chinese medicine(TCM) has a long history and has been scientific and advanced all the time.Treatment based on syndrome differentiation is the core thinking process of TCM intervention in the unhealthy state of the body，which is inherited and innovatively developed by syndrome differentiation-based health care.Postmenopausal osteoporosis has the clinical characteristics of insidious onset，high morbidity，and serious impact on the health and quality of life of patients.This paper，starting from the theory of syndrome differentiation-based health care，staged postmenopausal osteoporosis by trichotomy for the first time，established the diagnostic criteria for sub-health，conducted intervention through TCM syndrome classification，and determined corresponding rules and Chinese medicine measures for health care.Furthermore，together with comprehensive intervention approaches，the paper provided ideas and strategies for early detection，early intervention，and early benefit of postmenopausal osteoporosis，to reduce the incidence of the disease，improve the sub-health status of related high-risk groups，and promote the health of the whole people.