In recent years，traditional Chinese medicine(TCM) pharmaceutical industry has developed continuously，and initially formed an industrial system of a certain scale.It has become a strategic industry with great development advantages and broad market prospects in China's national economic and social development.However，for TCM clinical preparations，there are problems such as low technology，low production efficiency and low intelligentization，and the industrial development faces great pressure and challenges.Starting from the application of international cutting-edge technology in TCM clinical preparations，this paper systematically summarized and analyzed the problems existing in the manufacturing process of the prescriptions.Furthermore，the drug manufacturing equipment and manufacturing process were innovatively integrated based on the current situation of TCM clinical preparations，and an intelligent manufacturing system for TCM clinical preparations was proposed，which integrated comprehensive analysis of four examinations，syndrome differentiation and treatment，principle-method-recipe-medicinal，intelligent decision making，intelligent manufacturing，preparation-process-quality-efficacy，and personalized service.This paper was expected to provide reference for building an intelligent operation platform for TCM clinical preparations.