Lipid metabolism reprogramming has become a hot spot in tumor research.Abnormal lipid metabolism is closely related to the occurrence and development of malignant tumors，and regulating abnormal lipid metabolism pathways can effectively prevent and treat malignant tumors.However，related drugs are still under research and development.According to the theory of traditional Chinese medicine，abnormal lipid metabolism is equivalent to “turbid evil”(the accumulation of phlegm，dampness，blood stasis and other evil qi).It is not only a pathogenic factor，but also a pathological product，which runs through the occurrence and development of malignant tumors.In addition，the occurrence of “turbid evil” is also consistent with malignant tumors' deficiency in origin and excess in superficiality，and the “Strengthening Healthy Qi to Eliminate Pathogens” method can effectively inhibit the growth of malignant tumors and regulate abnormal lipid metabolism.Based on this，this article，focusing on lipid metabolism reprogramming，explores the application and potential mechanism of the “Strengthening Healthy Qi to Eliminate Pathogens” method in treating malignant tumors and regulating abnormal lipid metabolism(eliminating the “turbid evil”).