Ulcerative colitis(UC) is a common chronic disease in the digestive tract，which is difficult to cure.Traditional Chinese medicine(TCM) has unique advantages in the treatment of UC and has achieved definite clinical efficacy，but the specific mechanism is still unclear.With the rapid development of bioinformatics，network pharmacology is applied to explore the mechanism of TCM in the treatment of diseases.It can elaborate the pharmacological mechanism of TCM from multiple systems，which is consistent with the holistic view of TCM.According to the research ideas of network pharmacology，this paper summarized the current application of classic TCM prescriptions in the treatment of UC to provide new ideas for the modern development and application of TCM in the prevention and treatment of UC and further expound the scientific connotation of TCM theory.