Parkinson's disease(PD) is the second largest degenerative disease of the central nervous system.Since PD requires lifelong management，the high costs of treatment，rehabilitation，and nursing have caused heavy social and economic burden.According to the theory of traditional Chinese medicine，PD is a tremor syndrome with the main pathogenesis of liver-kidney yin deficiency.Liuwei Dihuang Pills，a classic yin tonic，has the effect of nourishing yin and liquid in the liver and kidney.Modern research suggests that this prescription has antioxidant，anti-aging，and immunomodulatory effects.Liuwei Dihuang Pills can delay the disease procession and reduce the dosage of western medicine in the treatment of PD with mild side effects.This review summarized the efficacy of Liuwei Dihuang Pills in the treatment of PD with the syndrome of liver-kidney yin deficiency，with a view to providing a theoretical basis for the treatment of PD.