This article summarized the experience of Professor Xiao Chengcong，a renowned traditional Chinese medicine(TCM) master，in improving follicular development in polycystic ovary syndrome(PCOS) with Qizi Yishen Lichong Decoction.Kidney deficiency and diminished thoroughfare vessel are the fundamental pathogenesis of follicular development disorders in PCOS.Kidney deficiency leads to insufficient essence and blood，which hampers their flow，while diminished thoroughfare vessel results in inadequate blood supply to the “sea of blood”，thus failing to nourish the follicles and leading to follicular development disorders.Professor Xiao advocated to take the therapeutic principles of nourishing the kidneys and regulating thoroughfare vessels，with a focus on identifying the ovulatory period and emphasizing psychological guidance.The commonly used formula is the self-formulated Qizi Yishen Lichong Decoction with modifications.