In recent years，the incidence of fatty liver has been gradually increasing，which has had a significant impact on people's life.There is still insufficient understanding of this disease in clinical practice，and the establishment of animal models for evaluating concordance is the basis for its research.Based on the disease and syndrome characteristics of fatty liver in traditional Chinese medicine(TCM) and western medicine and consulting clinical diagnostic criteria，the existing animal models of fatty liver were analyzed to propose diagnostic criteria in TCM and western medicine and their concordance was evaluated.The analysis results showed that the existing models mainly consisted of non-alcoholic and alcoholic models，with non-alcoholic models being primarily western medicine models and alcoholic models being predominantly TCM syndrome models.Western medicine treatment was in the early clinical stage and lacked effective prevention and treatment methods，while TCM treatment had a long history and a thorough understanding of fatty liver.In the future，it is necessary to improve the alcoholic western medicine models and non-alcoholic TCM syndrome models to provide a theoretical basis for investigating new disease treatment methods，developing new drugs，and early prevention and treatment of fatty liver.