To systematically evaluate the distribution of nine traditional Chinese medicine(TCM) constitutions in patients with depression and to preliminarily clarify the distribution patterns of TCM constitutions in patients with depression，providing a reference for the prevention and treatment of depression from the perspective of constitutions.Methods:China National Knowledge Infrastructure(CNKI)，China Science Periodical Database(CSPD)，Chinese Citation Database(CCD)，and PubMed were searched for relevant literature on TCM constitutions in depression.R software was used for Meta-analysis of single rates，and RevMan 5.3 software was used to conduct separate Meta-analyses for subgroups based on disease status and severity.The results were expressed as distribution rates，odds ratios(OR)，and their 95% confidence intervals.Results:Fourteen studies involving 10 484 participants were included.Among the depression population，the prevalence of the qi stagnation constitution was 27%，and the prevalence of the qi deficiency constitution was 26%.In the subpopulation with subthreshold depression，the prevalence of the qi stagnation constitution was 38%，and the prevalence of the qi deficiency constitution was 20%.The inter-group comparison revealed the prevalence of the qi stagnation and qi deficiency constitutions was significantly higher in the depression group than in the non-depression group.Conversely，the prevalence of the balanced constitution was significantly higher in the non-depression group than in the depression group.The prevalence of the qi deficiency constitution was significantly higher in the moderate-to-severe depression group than in the subthreshold depression group，showing a statistically significant difference.The overall quality of the literature was low，and there was a risk of bias.Conclusion:The qi stagnation and qi deficiency constitutions are the main constitution types in the depression population，showing significant differences compared with the non-depression population.The qi deficiency constitution is more common in the moderate-to-severe depression population，which may serve as an entry point for constitution-based prevention and treatment of depression.