To analyze the clinical characteristics and rules of acupoint selection in acupuncture and moxibustion treatment for post-stroke cognitive impairment.Methods:Relevant literature on acupuncture and moxibustion treatment for post-stroke cognitive impairment from January 1，2011，to May 31，2021，was searched in the China National Knowledge Infrastructure(CNKI)，China Science Periodical Database(CSPD)，and Chinese Citation Database(CCD).An Excel of acupuncture and moxibustion prescription database was established，and SPSS 26.0 and SPSS Modeler 18.0 software were used for statistical analysis to identify the rules of acupoint selection.Results:Seventy-seven clinical research articles were included，covering 77 acupoint prescriptions，85 acupoints，and a total frequency of 587 applications.The three most frequently used meridians and collaterals were the governing vessel，gallbladder meridian of foot lesser yang，and bladder meridian of foot greater yang.The majority of acupoints were located in the head，face，and neck regions，accounting for 47.53%，followed by the lower extremities，accounting for 27.26%.Specific acupoints such as confluence points，five transport points，and collateral points were widely used.Baihui(GV20) was the most frequently selected acupoint，with a frequency of 66 times.The combination of Baihui(GV20) and Sishencong(EX-HN1) showed the highest correlation among the selected acupoints.Conclusion:Acupuncture treatment for post-stroke cognitive impairment primarily focuses on local acupoint selection，supplemented by distal acupoints along the meridians.The use of confluence points is emphasized to enhance the connection between the governing vessels and the twelve regular meridians.