To summarize and clarify the functions and indications of Jujubae Fructus in classical TCM prescriptions and provide ideas and references for its clinical application.Methods:The 72 prescriptions containing Jujubae Fructus in the Treatise on Cold Damage and Miscellaneous Diseases were reviewed in detail in terms of usage，dosage，main indicated symptoms，and compatibility，and thus the application patterns of Jujubae Fructus were summarized.Results:The application amount of Jujubae Fructus in each prescription was mainly described in the number of fruits，and 12 was a common number in the prescriptions.Most of the prescriptions containing Jujubae Fructus were decoctions，in which Jujubae Fructus was used with the removal of pit，and a few prescriptions were paste or pills.The prescriptions containing Jujubae Fructus were mainly used to treat the diseases in head，face，chest，stomach，intestines，limbs，nutrient，and blood，which were mainly associated with cold，heat，pain，vomiting，and diarrhea.Jujubae Fructus in combination with Zingiberis Rhizoma Recens has the function of regulating the nutrient，defense，and qi movement.Jujubae Fructus in combination with Ginseng Radix et Rhizoma and Glycyrrhizae Radix et Rhizoma has the effect of tonifying the middle energizer and nourishing the nutrient.Jujubae Fructus in combination with Angelicae Sinensis Radix has the effect of tonifying blood，dredging vessels，tranquilizing mind，benefit earth and control water，and moderate the medicinal properties.Jujubae Fructus in combination with Kansui Radix，Genkwa Flos，and Descurainiae Semen/Lepidii Semen has the effect of expelling water，excreting water，reducing toxicity，and moderating medicinal properties.It should be used with caution in the cases of cough，chest and abdominal fullness，and phlegm obstruction.Conclusion:The efficacy of Jujubae Fructus varies depending on the compatibility and dosage，so it should be used reasonably based on syndrome differentiation in clinical practice.