Based on the constitution theory of traditional Chinese medicine(TCM)，the TCM treatment principles of “unidentifiable” pulmonary nodules were discussed，and it is believed that the occurrence and development of pulmonary nodules were closely related to the four basic principles of the TCM constitution theory.The treatment would be performed from identifying and improving the biased constitution，to diagnose and treat pulmonary nodules early through the thinking of “constitution identification and treatment”，thereby achieving the effect that “only when yin is at peace and yang is compact can essence-spirit be normal” and the purpose of “prevention before disease onset and controlling development of existing disease”.This paper provides new ideas and methods for TCM treatment of pulmonary nodules.