Chronic urticaria(CU) is one of the common diseases in clinical dermatology，with sudden wheals and erythema，accompanied by varying degrees of itching，or angioedema as the main manifestations.It has multiple，recurrent，and prolonged clinical characteristics，bringing great trouble to the patient's life.Its pathogenesis is still unclear，and many scholars believe that the imbalance of the immune system is the main cause of CU.Acupuncture has been widely proven to be an effective means of treating CU in clinical practice.Through literature review，acupuncture can mobilize the body's immune system through a variety of targets，inhibit mast cell degranulation，reduce autoantibody levels and the release of inflammatory mediators，and correct immune cell imbalance.In addition，acupuncture of the skin can inhibit the aggregate of local immune cells in skin lesions and reduce inflammatory cell infiltration，thereby promoting self-repair and improving the clinical symptoms of CU patients.