Secondary glomerular disease is a frequently-occurring disease that seriously affects human life and health.Traditional Chinese medicine attributes the key pathogenesis of such diseases to the failure of ascending clear yang and descending turbid yin.The main affected organs are lung，spleen and kidney.Tangible pathological products such as blood stasis and phlegm-dampness paly a crucial role in damaging the kidneys and influencing the progression of the disease.Conventional treatments for these diseases are often complicated，lengthy，and associated with fluctuating symptoms and high recurrence rates，traditional Chinese medicine，focused on the holistic perspective based on syndrome differentiation，employs the principle of ascending clear and descending turbidity in treatment，including regulating the spleen and kidney to assist in ascending and descending，connecting the heart and kidney for transportation and distribution，promoting the circulation of qi to facilitate ascending and descending，nurturing righteous qi to aid in ascending and clearing，eliminating pathogenic factors to descend turbidity，and utilizing the properties and tastes of herbs to assist in ascending and descending..This approach can not only improve the patient's conditions and enhance clinical efficacy，but also is of great significance to broaden the scope of disease treatment and highlight the unique characteristics of traditional Chinese medicine.