To study the modeling characteristics and index characteristics of benign prostatic hyperplasia in rats,and to provide reference and basis for the improvement of the efficiency of experimental modeling and scientific evaluation of drug prevention and treatment.Methods:A total of 228 literatures on animal models of benign prostatic hyperplasia in rats from January 2001 to February 2023 were collected from the China National Knowledge Infrastructure(CNKI) database.The information of animal type,modeling drug,positive control drug,test drug,drug administration time,dosage,administration method and site,evaluation index and test index were recorded and analyzed.Results:It is recommended to select SD male rats.The modeling scheme is to remove the bilateral testes of rats and inject testosterone propionate 3 to 5 mg/kg intraperitoneally for 30 days,once a day.Common indicators include tissue biochemical indicators,serum biochemical indicators,prostate histopathological indicators,and so on.Finasteride is the main therapeutic drug.The commonly used traditional Chinese medicine compounds are Xianjia decoction,Longchang capsule and Jiawei Guizhi Fuling granule.The administration period is about 30 days.Conclusion:Through analysis and discussion,it can be concluded that the efficient and accurate modeling method is of significance for the modeling and treatment of benign prostatic hyperplasia in animals.