Artemisia argyi leaf is one of the most common traditional Chinese medicines in daily life and clinical practice,with characteristics such as wide adaptation scenarios and excellent therapeutic effects.The ancient medical literature summarized the efficacy of Artemisia argyi leaf into two major functions:dispersing cold and relieving pain,warming meridians and stopping bleeding,which is clinically used in the treatment of diseases such as lower energizer deficiency cold and woman's blood syndrome.In recent years,studies have found that Artemisia argyi leaf has the effects of antibacterial and antiviral,blood coagulation and hemostasis,anti-tumor,cough and asthma relief,analgesia and anti-inflammatory,liver protection and promotion of gallbladder function,blood glucose and lipid regulation,and so on,which can be used in the treatment of pregnancy vomiting,hyperlipidemia,diabetes,cancer and other diseases.This article uses VOSviewer visualization software to construct a knowledge graph and analyzes the ancient and modern evolution of the medicinal,dietary,topical,and pharmacological effects of Artemisia argyi leaf from five aspects including the properties,taste,composition and compatibility rules,clinical application,and modern pharmacological effects,indicating.By combining the ancient traditional effects of Artemisia argyi leaf with modern pharmacological research,this paper provides ideas for the modern research and innovative transformation of Artemisia argyi leaves.