不同针刺法联合言语训练治疗卒中后失语的网状Meta分析
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国家重点基础研究发展计划(“973”计划)项目(2018YFC1706001)


Network Meta-analysis of Different Acupuncture Methods Combined with Speech Training for Treatment of Post-stroke Aphasia
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    摘要:

    目的:评价不同针刺法分别联合言语训练治疗卒中后失语(Post-stroke Aphasia,PSA)的有效性。方法:检索国家知识基础设施数据库(CNKI)、中国生物医学文献数据库(CBM)、中国学术期刊数据库(CSPD)、中文科技期刊数据库(CCD)、PubMed、Embase和Cochrane Library数据库自建库至2022年6月所发表的头针、舌针、眼针及醒脑开窍针刺法治疗卒中后失语患者的临床随机对照试验(RCTs)。由2位研究者独立筛选文献、资料提取和偏倚风险评价,应用RevMan5.3、Stata16.0、ADDIS1.16.8软件进行数据分析。结果:共检索出1 618篇文献,最终纳入26项研究,共1 815例患者。干预措施均为头针、舌针、眼针及醒脑开窍针刺法中的一项联合言语训练的对照研究。网状Meta分析结果显示:不同针刺方法联合言语训练在失语疗效方面要优于单纯应用言语训练,眼针联合言语训练在提升治疗卒中后失语有效率方面最优;醒脑开窍针法在改善患者失语商(AQ)评分及CFCP评分方面最优;醒脑开窍针法在降低患者NIHSS评分方面最优。结论:在言语训练基础上,联合使用不同针刺方法可增加卒中后失语患者治疗的临床疗效,然不同针刺方法在改善AQ评分、CFCP评分及NIHSS评分方面具有相对优势,但受限于符合条件的研究数量和质量,上述结论需要更多标准化、严谨、高质量的临床试验进一步验证。

    Abstract:

    To evaluate the effectiveness of different acupuncture methods combined with speech training in the treatment of post-stroke aphasia(PSA).Methods:CNKI,CBM,CSPD,CCD,PubMed,Embase,and Cochrane Library were searched from their establishment to June 2022 for randomized controlled clinical trials(RCTs) of scalp acupuncture,tongue acupuncture,eye acupuncture,and Xingnao Kaiqiao acupuncture in the treatment of PSA patients.Literature selection,data extraction,and bias risk assessment were independently conducted by two researchers.RevMan5.3,Stata16.0,and ADDIS1.16.8 software were used for data analysis.Results:A total of 1 618 articles were retrieved,and 26 studies were eventually included,with a total of 1 815 patients.The intervention measures were controlled studies with scalp acupuncture,tongue acupuncture,eye acupuncture,or Xingnao Kaiqiao acupuncture combined with speech training.The results of the network Meta-analysis showed that different acupuncture methods combined with speech training were better than speech training alone in the treatment of aphasia,and eye acupuncture combined with speech training had the best effective rate in improving PSA.Xingnao Kaiqiao acupuncture was the best in improving the AQ and CFCP scores and reducing NIHSS scores of PSA patients.Conclusion:On the basis of speech training,the combination of different acupuncture methods can increase the clinical efficacy of the treatment of PSA patients.However,different acupuncture methods have certain advantages in improving the AQ score,CFCP score,and NIHSS score,but they are limited by the number and quality of eligible studies.The above conclusions need to be further verified by more standardized,rigorous,and high-quality clinical trials.

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朱巍明,李波漩,邓士哲,迟世浩,孟智宏.不同针刺法联合言语训练治疗卒中后失语的网状Meta分析[J].世界中医药,2024,(03).

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  • 收稿日期:2022-10-08
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  • 在线发布日期: 2024-05-08
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