To systematically evaluate the clinical efficacy of eight classical prescriptions combined with conventional western medicine in the treatment of unstable angina pectoris(UAP) by network meta-analysis and compare their effects on sthenia syndromes or asthenia syndromes(including asthenia and sthenia syndromes).Methods:Randomized controlled trials(RCTs) on the treatment of UAP with eight classical prescriptions(Xuefuzhuyutang，Buyanghuanwutang，Simiaoyongantang，Danshenyin，Zhigancaotang，Zhishixiebaiguizhitang，Gualouxiebaibanxiatang，and Huatanquyutongmaitang) combined with conventional western medicine were retrieved from Chinese Citation Database(CCD)，China Biology Medicine(CBM)，China National Knowledge Infrastructure(CNKI)，and China Science Periodical Database(CSPD) from the establishment to January 14，2022.Stata 16.0 software was used for network Meta-analysis.Results:A total of 60 RCTs were included，involving 5 090 patients with UAP and nine intervention measures.Among them，there were 41 RCTs of sthenia syndromes and 3 466 UAP patients，involving five kinds of interventions.There were 13 cases of asthenia syndromes or asthenia and sthenia syndromes with 1 130 patients，involving four kinds of interventions.The results of the network Meta-analysis suggested that the total effective rate of Zhishixiebaiguizhitang+conventional western medicine was the best.For UAP patients with sthenia syndromes，Simiaoyongantang+conventional western medicine had the optimal treatment effects.For patients with asthenia syndromes or asthenia and sthenia syndromes，Buyanghuanwutang+conventional western medicine was the best.In terms of electrocardiogram，Buyanghuanwutang had the best improvement，and Zhishixiebaiguizhitang+conventional western medicine had the best effect in reducing high-sensitivity C-reactive protein(hs-CRP) and improving inflammatory response.Conclusion:Zhishixiebaiguizhitang+conventional western medicine was more effective than conventional western medicine alone in the treatment of UAP.However，this study needs to be further verified by more high-quality RCTs.