Currently,hematopoietic stem cell transplantation(HSCT) is considered the only possible cure for malignant hematological diseases.However,poor implantation,many transplantation-related complications,and high relapse rates seriously affect the survival rate and quality of life of patients,which are now not fully addressed by Western medicine.By summarizing the literature on traditional Chinese medicine(TCM) intervention in HSCT,it was recognized that TCM played a synergistic and complementary role in multiple aspects of HSCT.TCM combined with HSCT can regulate the patient's constitution before transplantation,improve the quality of hematopoietic stem cell mobilization and collection,facilitate transplantation pretreatment,and promote hematopoietic reconstitution.It can also effectively prevent complications and relapse.Therefore,TCM combined with HSCT has a very broad developmental prospect.