TCM guidance combining physical exercise and breathing and mental regulation can modulate the essence，qi，and spirit of the human body，with the effects of harmonizing yin and yang，preventing and treating diseases，and prolonging life.Perimenopausal symptoms include hot flash，irritability，feverish feeling in palms and soles，tinnitus，palpitation，dizziness，insomnia，amnesia，mental burnout，low back pain，and menstrual disorder，demonstrating negative effects on the physical and psychological health of women in the perimenopausal period.TCM guidance is a characteristic method for treating postmenopausal symptoms.It can not only alleviate the local physical symptoms but also regulate the qi，blood，zang-fu organs，and yin and yang to restore the body harmony of women in the perimenopausal period.