To investigate the chemical constituents in the ethyl acetate fraction of the fruit extract of Daemonorops draco Bl.and their platelet-inhibitory activities.Methods:The ethyl acetate fraction of the fruit extract of D.draco was separated and purified by column chromatography with silica gel，ODS，and Sephadex LH-20 and semi-preparative HPLC.The structures of the chemical constituents were identified based on the spectral data from 1H-NMR，13C-NMR，and MS.The ATP release from thrombin-activated platelets was employed to screen the active constituents.Results:Eleven compounds were obtained from the ethyl acetate fraction of the fruit extract of D.draco.They were identified as ethyl 4,6-dihydroxy-2-methoxy-3-methylbenzoate(1)，6-hydroxy-2,4-dimethoxy-3-methyl phenylethanol(2)，4,6-dihydroxy-2-methoxy-3-methyl benzaldehyde(3)，ethyl p-hydroxy benzoate(4)，methyl 4-hydroxy benzoate(5)，3,5-dichlorosalicylic acid(6)，p-hydroxybenzaldehyde(7)，pinocembrin(8)，strobopinin(9)，7-hydroxy-5-methoxy-6-methylflavanone(10)，and ozoroalide(11).Conclusion:Compound 1 was a new compound and compounds 2 and 3 were new natural products.Compounds 3，7，and 9 significantly inhibited the ATP release from thrombin-activated platelets.