新外来中药白果槲寄生的中药药性探讨
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国家中医药管理局国际合作司中医药国际合作专项(基地类项目)(0730-236132ZC0054/01~03);国家中医药管理局国际合作司中医药国际合作专项(中心类项目)(0730-236132ZC0052/01~04)


Chinese Medicine Properties of New Exotic Chinese Medicine Viscum album L.
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    摘要:

    白果槲寄生是桑寄生科槲寄生属白果槲寄生(Viscum album L.)的新鲜带叶茎枝和果实,中国无分布。在欧洲被广泛应用于癌症的治疗,被列入《美国顺势疗法药典》《德国顺势疗法药典》等。目前,以白果槲寄生提取物为主要原料的海利升注射液已作为进口的天然药物进入我国临床,主要用于肺癌、乳腺癌、卵巢癌辅助治疗。通过总结分析白果槲寄生科学研究文献,结合中医理论对其中药药性进行探讨。通过对白果槲寄生的活性成分、临床应用、药理作用等文献分类研究,归纳出白果槲寄生具有抗癌和提高癌症患者生命质量、降血糖、降血压、抗氧化、抗癫痫等药理作用;依据临床应用和使用情况,结合中药药性理论,经过综合分析研究赋予了白果槲寄生中药药性。白果槲寄生的性味归经为性平味甘;归肝、肾、脾经。功效为解毒散结、平肝潜阳、益气养阴,可用于治疗癥瘕积聚,肝阳上亢,痫证,津伤口渴,内热消渴等。供配制成药用(皮下注射),建议从1 mL 0.000 1 mg开始,每周注射次数根据患者情况决定。

    Abstract:

    The fresh stems,branches,and fruits with leaves of (Viscum album L.)in the family Santalaceae are medicinal parts and V.album is not distributed in China.Widely used in Europe for cancer treatment,V.album is listed in the Homeopathic Pharmacopoeia of the United States and German Homoeopathic Pharmacopoeia.Currently,Helixor A injection,mainly derived from V.album extract,has been imported into China as a natural medicine for clinical use,primarily in adjunctive therapy for lung cancer,breast cancer,and ovarian cancer.By summarizing and analyzing scientific research literature on V.album and in combination with traditional Chinese medicine(TCM) theory,this study explored its medicinal properties.Through classified investigation on active ingredients,clinical applications,pharmacological effects,etc.of V.album,it is concluded that V.album has pharmacological effects such as anticancer properties,improving quality of life in cancer patients,lowering blood sugar,reducing blood pressure,antioxidative effects,and antiepileptic effects.Based on its clinical applications,usage,and TCM theory,V.album is characterized with the following properties:neutral in nature and sweet in flavor,and acting on the liver,kidney,and spleen meridians.It has functions include removing toxin,dissipating masses,pacifying liver,subduing yang,replenishing qi,and nourishing yin,and can be used to treat abdominal mass,ascendant hyperactivity of liver yang,epilepsy,thirst due to fluid damage,and internal heat with thirst.For preparation as a medicinal product(subcutaneous injection),it is recommended to start with 1 mL of 0.000 1 mg and adjust the frequency of injections weekly based on the patient's condition.

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热依塞·努尔买买提,梁唯灿,李一芃,邸松蕊,付祥郴,王梓旭,王淳,郭宝林,王林元,朱映黎,张建军.新外来中药白果槲寄生的中药药性探讨[J].世界中医药,2024,(11).

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  • 收稿日期:2024-04-10
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  • 在线发布日期: 2024-07-24
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