Panvascular disease is a common complication of type 2 diabetes mellitus(T2DM) and an important cause of disability and death in patients with T2DM.Therefore，delaying the progression of T2DM complicated with panvascular disease is the focus of clinical attention.Modern theoretical research mostly attributes T2DM to Xiaoke diabetes.This paper analyzed the etiology，pathogenesis，and mechanism of T2DM complicated with panvascular disease and investigated the pathogenesis of Xiaoke diabetes heart disease，Xiaoke diabetes kidney disease，and Xiaoke diabetes eye disease.The core of the disease was determined to be blood stasis syndrome，and blood stasis is its pathological product throughout the disease development.