Based on the disease-syndrome characteristics and diagnostic criteria of diabetic gastroparesis(DGP) in both traditional Chinese medicine(TCM) and Western medicine,this study summarized existing animal models of DGP,analyzed their features,and explored future directions for model development,providing insights for the creation of new DGP animal models.Methods:By conducting a literature review,the characteristics of various animal models were summarized,and clinical diagnostic standards from both TCM and Western medicine were established.Symptoms and relevant indicators of the models were evaluated to assess their alignment with clinical manifestations.Results:Among the included studies,the most frequently used animals were Sprague-dawley(SD) rats(114 times) and Wistar rats(34 times),with male animals being the predominant choice.After assigning values to the animal models,the modeling method that most closely matched clinical presentations involved the injection of STZ combined with a high-sugar,high-fat diet or oral administration of Rehmanniae Radix Praeparata decoction,with TCM and Western medicine alignment rates of 80% and 95%,respectively.Spontaneous DGP animal models showed lower alignment with clinical characteristics in both TCM and Western medicine,with the lowest alignment found in ob/ob mice,with rates of 10%(TCM) and 35%(Western medicine).Genetically engineered DGP mouse models also demonstrated low clinical alignment,with both TCM and Western alignment rates≤50%.Conclusion:Current DGP animal models mainly include induced,spontaneous,and gene knockout types.The most widely used model,with the highest alignment to both TCM and Western clinical manifestations,is the STZ-induced model that destroys pancreatic β-cells combined with a high-sugar,high-fat diet.Other animal models generally show lower alignment with TCM characteristics,failing to fully represent TCM syndromes.