Gastric mucosa atrophy and intestinal metaplasia have been classified as gastric precancerous states in 2020，contributing to a new disease classification.In response to the change in disease spectrum and modern lifestyle，the academic viewpoint of “liver and spleen harmonization，dredging and construction of middle jiao” was advocated，and the “liver turbidity” was innovatively enriched to deepen the theory of “liver stagnation leads to turbidity and toxin”.By taking the disease and syndrome thinking as the main line，clinical practice was guided，and the treatment principle of “following the regularity with dredging the liver，nipping in the bud with tonifying the kidney，and eliminating external evils with relieving the turbidity” was established.On this basis，the Xinganpi Jiuwei Prescription based on Chaihu Shugan Powder and Pingwei Powder was developed.It is necessary to pay attention to the transformation of inflammation to cancer and implement the new management model that “long-term medical treatment may not take long-term medicine，and chronic disease management cannot be considered as chronic disease treatment”.