Depression is a disorder characterized primarily by significant and persistent low mood，with fatigue identified as one of its core symptoms.Fatigue may persist as a residual symptom throughout a person's life，significantly increasing the rate of relapse in depression.The main pathogenesis of depressive fatigue is related to liver qi stagnation and yang deficiency.Moxibustion，which has the effects of warming meridians，dredging collaterals，and tonifying qi and blood，may therefore be an effective treatment for improving fatigue in depression.