Thromboangiitis obliterans(TAO) is an inflammatory，segmental，non-atherosclerotic disease affecting small and medium-sized arteries and veins.The pathogenesis is complex and closely related to oxidative stress，inflammation，immune dysfunction，endothelial dysfunction，and genetic abnormalities.Currently，in Western medicine，when pharmacological interventions for this disease are not significantly effective，surgical methods such as vascular intervention，vascular reconstruction，bone transplantation for vascular regeneration，and sympathetic nerve resection are commonly used.These procedures provide pain relief but are associated with high recurrence and amputation rates.Traditional Chinese medicine(TCM)，with its characteristics of multi-component，multi-target，and multi-pathway approaches to disease prevention and treatment，has shown good clinical efficacy in managing TAO.Extensive research has demonstrated that the potential mechanisms by which TCM prevents and treats TAO involve reducing oxidative stress，exerting anti-inflammatory effects，regulating immunity，protecting endothelial function，and improving blood rheology.