《中华人民共和国药典》中药非药用部位现代研究及综合应用情况
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国家自然科学基金项目(82074038);河南省重大专项(221100310400);河南省国际合作重点项目(231111521200)


Modern Research and Comprehensive Application of Non-medicinal Parts of Chinese Medicines in Chinese Pharmacopoeia
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    摘要:

    目的:统计并分析2020年版《中华人民共和国药典》中药非药用部位的现代研究和综合应用情况,为非药用部位的进一步研究和开发利用提供数据支持。方法:根据《中华人民共和国药典》中药及其药用部位记载,从《中药大辞典》筛选出非药用部位,统计中药非药用部位基原、化学成分、药理作用、临床应用,并进行频次分析。结果:196味中药具有非药用部位,其科属以菊科、蔷薇科、豆科植物多见,非药用部位以根、叶、花多见,化学成分以黄酮类、酚类、挥发油多见,药理作用以抗氧化、抗肿瘤、抗炎频次最高,临床多用于消化内科、皮肤科、神经内科疾病治疗。结论:我国非药用资源丰富,非药用部位中药应用潜力及开发价值巨大,但其存在现代研究不足,且多数非药用部位的开发利用尚未形成产业模式等问题。应加大非药用部位中药的现代研究及综合应用,建立非药用部位中药质量标准,完善非药用部位中药产业链,促进非药用部位中药高质量发展。

    Abstract:

    To statistically analyze and evaluate the modern research and comprehensive application of non-medicinal parts of Chinese medicines in the 2020 edition of the Pharmacopoeia of the People's Republic of China(hereinafter referring to Chinese Pharmacopoeia),providing data support for further research and development of non-medicinal parts.Methods:Based on the records of Chinese medicines and their medicinal parts in the Chinese Pharmacopoeia,non-medicinal parts were selected from the Dictionary of Chinese Medicine.The origin,chemical composition,pharmacological effects,and clinical applications of non-medicinal parts of Chinese medicines were statistically analyzed,with frequency analysis conducted.Results:A total of 196 Chinese medicines possess non-medicinal parts.These medicines predominantly belong to the Asteraceae,Rosaceae,and Leguminosae families.Non-medicinal parts are most commonly the root,leaf,and flower.Chemical components are primarily flavonoids,phenolic compounds,and volatile oils.The most frequent pharmacological actions include antioxidant,anti-tumor,and anti-inflammatory effects.Clinically,they are mainly used in the treatment of diseases in gastroenterology,dermatology,and neurology.Conclusion:China has abundant non-medicinal resources,and the potential and developmental value of non-medicinal parts of Chinese medicines are enormous.However,there is a lack of modern research,and the development and utilization of most non-medicinal parts have not yet formed an industrial model.It is essential to strengthen modern research and comprehensive application of non-medicinal parts,establish quality standards for non-medicinal parts of Chinese medicines,improve the industry chain,and promote the high-quality development of non-medicinal Chinese medicinal resources.

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吉晓妍,贺红娟,匡淑一,刘英峰,白明,李秀敏,苗明三.《中华人民共和国药典》中药非药用部位现代研究及综合应用情况[J].世界中医药,2024,(23).

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  • 收稿日期:2024-03-04
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  • 在线发布日期: 2025-03-05
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