血管衰老与老年泛血管疾病的关系及其中西医结合防治策略
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中国中医科学院科技创新工程重大攻关项目(CI2021A01406)


Vascular Aging and Pan-vascular Disease in the Elderly:Reflections on the Prevention and Treatment Strategy of Integrated Traditional Chinese and Western Medicine
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    摘要:

    血管衰老以血管功能障碍和脉管系统结构老化为特征,是引起人体各系统、各器官衰老的重要病理基础。泛血管疾病是一组以动脉粥样硬化为共同病理特征的血管系统疾病。血管衰老在泛血管疾病的发生发展中起关键作用。衰老血管为泛血管疾病的发生发展提供了环境,而泛血管疾病又反过来加速血管衰老的进程,二者互为因果。中医药从血管衰老中医病机阐释老年泛血管疾病,从血管衰老防治泛血管疾病。中西医结合延缓血管衰老防治泛血管疾病的策略包括辨识血管健康状态与风险因素促进泛血管疾病防治关口前移,建立病证结合干预模式减轻血管衰老、阻断泛血管疾病进展,开展多学科交叉融合的系统性防控与个性化干预。为今后中西医结合延缓血管衰老相关泛血管疾病提供思路。

    Abstract:

    Vascular aging is characterized by vascular dysfunction and the structural aging of the vascular system,serving as an important pathological basis for the aging of various systems and organs in the body.Pan-vascular diseases refer to a group of vascular system diseases characterized by a common pathological feature of atherosclerosis.Vascular aging plays a key role in the occurrence and progression of pan-vascular diseases.Aging blood vessels provide an environment for the onset and development of pan-vascular diseases,while pan-vascular diseases,in turn,accelerate the process of vascular aging.Both are interdependent.Traditional Chinese medicine(TCM) explains the pathogenesis of pan-vascular diseases in the elderly from the perspective of vascular aging and provides strategies for the prevention and treatment of these diseases.The integrated approach of TCM and Western medicine in delaying vascular aging and preventing pan-vascular diseases includes identifying vascular health status and risk factors to promote early intervention in the prevention and treatment of pan-vascular diseases,establishing an intervention model that combines diseases and syndromes to reduce vascular aging and block the progression of pan-vascular diseases,and conducting interdisciplinary,systematic prevention and personalized interventions.This study is expected to provide ideas for the future integration of TCM and Western medicine to delay vascular aging-related pan-vascular diseases.

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王青,刘艳飞,徐仕晗,刘凤岚,刘玥,徐凤芹.血管衰老与老年泛血管疾病的关系及其中西医结合防治策略[J].世界中医药,2024,(23).

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  • 收稿日期:2023-08-02
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  • 在线发布日期: 2025-03-05
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